Polynucleotides vs. Microneedling with NCTF Serum: Which Skin Rejuvenation Treatment Is Right for You?

If you’re looking to refresh dull, tired skin and restore a smoother, more radiant complexion, two advanced skin treatments are leading the way in 2025: Polynucleotides and Microneedling with NCTF® Serum.

Both are powerful, non-surgical options for skin rejuvenation — but they work in different ways and are best suited to slightly different skin concerns.

In this guide, we’ll break down what each treatment does, who it’s for, and how to choose the right one for your skin goals.

🔬 What Are Polynucleotides?

Polynucleotides are bioactive molecules derived from DNA fragments that stimulate the skin’s natural regeneration process. When injected into the skin, they:

• Boost collagen and elastin production

• Deeply hydrate and improve skin elasticity

• Repair damaged tissue and reduce inflammation

• Support healing for pigmentation, sun damage, and scarring

Think of polynucleotides as a “reset button” for your skin cells, helping them behave like younger, healthier versions of themselves.

✅ Key Benefits of Polynucleotides:

• Improves skin tone, texture, and elasticity

• Reduces fine lines and early signs of ageing

• Enhances hydration and glow from within

• Supports healing of acne scars and sun damage

• Strengthens the skin barrier over time

🔍 Best For:

• Dull, dehydrated, or tired-looking skin

• Clients seeking long-term, regenerative results

• Subtle, natural improvement in skin quality

• Ageing prevention and skin strengthening

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✨ What Is Microneedling with NCTF® Serum?

Microneedling (also known as collagen induction therapy) uses ultra-fine needles to create microchannels in the skin, triggering your body’s natural healing response.

When combined with NCTF® 135 HA — a potent mesotherapy serum containing hyaluronic acid, vitamins, amino acids, minerals, and coenzymes — the treatment delivers targeted skin nutrition deep into the dermis, where it's needed most.

✅ Key Benefits of Microneedling with NCTF®:

• Stimulates collagen and elastin for firmer skin

• Refines pores and smooths uneven texture

• Reduces acne scarring, pigmentation, and fine lines

• Boosts hydration and radiance

• Improves overall skin tone and clarity

🔍 Best For:

• Uneven skin texture, acne scarring, enlarged pores

• Clients needing a fast skin refresh or pre-event glow

• Fine lines, dullness, and dehydration

• Younger clients or those new to skin treatments

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🆚 Polynucleotides vs. Microneedling with NCTF®: Which One Should You Choose?

Here’s a quick comparison to help guide your decision:

If You Want...Choose...Long-term skin regeneration and repairPolynucleotidesFast improvement in texture, tone, and glowMicroneedling with NCTF®To treat scarring, pigmentation, and dullnessBoth treatments can be combined

In fact, many clients choose to combine both treatments in a personalised skin plan — using microneedling to resurface the skin and polynucleotides to repair and rebuild from within.

💡 Why Choose These Treatments Now?

Both polynucleotides and microneedling are non-invasive, clinically backed, and suitable for all skin types. And because they stimulate your skin’s natural renewal processes, results continue to improve over time.

Starting now means you’ll begin seeing visible results within 4–6 weeks, with optimal skin transformation in 12 weeks — just in time for spring and summer.

BOOK NOW

• Give us a call or drop us an email — we’d love to chat about your skin goals!

  Call: 07471565385

  Email: selfcare.aestheticservices@gmail.com

  I’m here to guide you every step of the way.